EA
EVENTIDE ASSET MANAGEMENT, LLC
EVENTIDE ASSET MANAGEMENT, LLC · Investor
1Y performance ⓘ
+27%
AUM (13F)
$6.0B
# of Holdings
278
3Y performance ⓘ
+56%
vs S&P 500 ⓘ
−23%
Updated
Mar 31
EVENTIDE ASSET MANAGEMENT, LLC's EVENTIDE ASSET MANAGEMENT, LLC holds 278 U.S.-equity positions worth $6.0B (SEC 13F, Q1 2026). Top positions: Guardant Health, Inc. Common Stock 3.6%, Trane Technologies plc 2.8%, Lam Research Corp 2.4%. 13F-replication return is +56% over 3 years (-23 pts vs the S&P 500) — a replicated, non-audited figure.
Holdings
| Stock | % of portfolio | Shares | Value | Latest activity | Avg buy price | Current price | Date |
|---|---|---|---|---|---|---|---|
| GH Guardant Health, Inc. Common Stock | 3.6% | 2.4M | $218M | ▼ 5.9% (−149K) | $29.03 | $177.00 (+510%) | 2026-03-31 |
| TT Trane Technologies plc | 2.8% | 407K | $169M | ▲ 0.8% (+3K) | $197.26 | $452.40 (+129%) | 2026-03-31 |
| LRCX Lam Research Corp | 2.4% | 688K | $147M | ▲ 2.9% (+19K) | $82.10 | $339.09 (+313%) | 2026-03-31 |
| MIRM Mirum Pharmaceuticals, Inc. Common Stock | 2.1% | 1.4M | $130M | ▼ 33% (−685K) | $27.31 | $86.09 (+215%) | 2026-03-31 |
| TRGP Targa Resources Corp. | 2.1% | 502K | $126M | ▲ 4.5% (+22K) | $115.56 | $268.58 (+132%) | 2026-03-31 |
| XMTR Xometry, Inc. Class A Common Stock | 2.0% | 3.0M | $121M | ▲ 0.8% (+24K) | $19.34 | $103.86 (+437%) | 2026-03-31 |
| GEV GE Vernova Inc. | 1.9% | 133K | $116M | ▼ 29% (−54K) | $330.99 | $953.30 (+188%) | 2026-03-31 |
| ODFL Old Dominion Freight Line | 1.9% | 592K | $115M | ▼ 3.1% (−19K) | $169.33 | $173.90 (+3%) | 2026-03-31 |
| SRRK Scholar Rock Holding Corporation Common Stock | 1.8% | 2.2M | $108M | ▼ 9.6% (−234K) | $17.79 | $48.52 (+173%) | 2026-03-31 |
| ARGX Argenx Se | 1.5% | 126K | $92M | ▲ 3.7% (+4K) | $417.35 | $966.82 (+132%) | 2026-03-31 |
| ASML Asml Hldg Nv | 1.5% | 68K | $90M | ▲ 1.9% (+1K) | $701.11 | $1,817.25 (+159%) | 2026-03-31 |
| IRTC iRhythm Holdings, Inc. Common Stock | 1.5% | 761K | $90M | ▲ 9.9% (+68K) | $94.36 | $114.18 (+21%) | 2026-03-31 |
| INSM Insmed, Inc. | 1.5% | 546K | $89M | ▲ 13% (+63K) | $56.80 | $115.23 (+103%) | 2026-03-31 |
| AXSM Axsome Therapeutics, Inc | 1.4% | 520K | $88M | ▼ 9.0% (−52K) | $77.83 | $184.72 (+137%) | 2026-03-31 |
| PCVX Vaxcyte, Inc. Common Stock | 1.3% | 1.4M | $80M | ▲ 50% (+457K) | $49.73 | $56.72 (+14%) | 2026-03-31 |
| ETR Entergy Corporation | 1.3% | 683K | $77M | ▲ 1.5% (+10K) | $78.83 | $98.38 (+25%) | 2026-03-31 |
| VST Vistra Corp. | 1.2% | 493K | $74M | ▲ 1.0% (+5K) | $82.98 | $141.01 (+70%) | 2026-03-31 |
| URI United Rentals, Inc. | 1.2% | 98K | $71M | ▲ 1.9% (+2K) | $682.64 | $995.40 (+46%) | 2026-03-31 |
| LBRT Liberty Energy Inc. | 1.1% | 2.4M | $69M | ▲ 22% (+433K) | $20.32 | $18.19 (−10%) | 2026-03-31 |
| TOST Toast, Inc. | 1.1% | 2.5M | $66M | — | $20.44 | $29.16 (+43%) | 2026-03-31 |
| MTD Mettler-Toledo International | 1.1% | 51K | $64M | ▲ 1.0% (+493) | $1,456.35 | $1,507.36 (+4%) | 2026-03-31 |
| MPWR Monolithic Power Systems, Inc. | 1.1% | 58K | $63M | ▼ 15% (−10K) | $662.21 | $1,345.12 (+103%) | 2026-03-31 |
| RPRX Royalty Pharma plc Class A Ordinary Shares | 1.0% | 1.3M | $63M | ▲ 1.2% (+16K) | $35.00 | $57.90 (+65%) | 2026-03-31 |
| NVT nVent Electric plc Ordinary Shares | 1.0% | 524K | $62M | ▲ 1.7% (+9K) | $45.26 | $160.53 (+255%) | 2026-03-31 |
| WMB Williams Companies Inc. | 1.0% | 832K | $61M | ▲ 4.9% (+39K) | $39.93 | $67.86 (+70%) | 2026-03-31 |
| NDAQ Nasdaq, Inc. Common Stock | 1.0% | 712K | $60M | ▲ 0.7% (+5K) | $76.00 | $92.45 (+22%) | 2026-03-31 |
| GNRC GENERAC HOLDINGS INC | 1.0% | 307K | $60M | ▲ 227% (+213K) | $182.99 | $206.50 (+13%) | 2026-03-31 |
| BBNX Beta Bionics, Inc. Common Stock | 1.0% | 5.9M | $60M | ▲ 19% (+951K) | $12.04 | $18.90 (+57%) | 2026-03-31 |
| DHI D.R. Horton Inc. | 1.0% | 431K | $59M | ▲ 0.9% (+4K) | $106.89 | $134.40 (+26%) | 2026-03-31 |
| KLAC KLA Corporation Common Stock | 1.0% | 40K | $58M | ▼ 12% (−6K) | $61.37 | $198.82 (+224%) | 2026-03-31 |
| BLTE Belite Bio Inc | 0.9% | 358K | $57M | ▼ 6.6% (−25K) | $116.13 | $169.83 (+46%) | 2026-03-31 |
| LSCC Lattice Semiconductor Corp | 0.9% | 611K | $57M | ▼ 1.6% (−10K) | $77.83 | $127.74 (+64%) | 2026-03-31 |
| PLD PROLOGIS, INC. | 0.9% | 427K | $56M | ▲ 1.5% (+6K) | $113.81 | $128.30 (+13%) | 2026-03-31 |
| TMDX TransMedics Group, Inc. Common Stock | 0.9% | 549K | $55M | — | $60.87 | $83.42 (+37%) | 2026-03-31 |
| DTM DT Midstream, Inc. | 0.9% | 402K | $54M | ▲ 1.8% (+7K) | $111.02 | $118.90 (+7%) | 2026-03-31 |
| NI NiSource Inc. | 0.9% | 1.1M | $53M | ▲ 0.9% (+10K) | $40.14 | $38.62 (−4%) | 2026-03-31 |
| KYMR Kymera Therapeutics, Inc. Common Stock | 0.9% | 627K | $52M | — | $35.21 | $113.05 (+221%) | 2026-03-31 |
| RBA RB Global, Inc. | 0.8% | 528K | $51M | — | $90.34 | $79.63 (−12%) | 2026-03-31 |
| WCN Waste Connections, Inc. | 0.8% | 310K | $50M | — | $139.36 | $154.03 (+11%) | 2026-03-31 |
| ORLY O'Reilly Automotive, Inc. | 0.8% | 540K | $50M | — | $59.92 | $85.07 (+42%) | 2026-03-31 |
| PWR Quanta Services, Inc. | 0.8% | 89K | $49M | ▲ 0.5% (+454) | $292.92 | $643.44 (+120%) | 2026-03-31 |
| COLL Collegium Pharmaceutical, Inc. Common Stock | 0.8% | 1.4M | $47M | ▼ 24% (−452K) | $24.03 | $21.95 (−9%) | 2026-03-31 |
| APGE Apogee Therapeutics, Inc. Common Stock | 0.8% | 557K | $47M | ▲ 28% (+121K) | $77.37 | — (+9%) | 2026-03-31 |
| VMC Vulcan Materials Company(Holding Company) | 0.8% | 170K | $46M | — | $233.79 | $243.05 (+4%) | 2026-03-31 |
| NVDA NVIDIA CORP | 0.7% | 259K | $45M | ▲ 8.4% (+20K) | $120.50 | $230.82 (+92%) | 2026-03-31 |
| EGP EastGroup Properties Inc. | 0.7% | 236K | $44M | — | $176.31 | $196.72 (+12%) | 2026-03-31 |
| IONS Ionis Pharmaceuticals, Inc. Common Stock | 0.7% | 575K | $43M | — | $70.81 | $45.57 (−36%) | 2026-03-31 |
| STE STERIS plc | 0.7% | 195K | $43M | ▲ 2.2% (+4K) | $209.41 | $209.75 (+0%) | 2026-03-31 |
| PANW Palo Alto Networks, Inc. Common Stock | 0.7% | 252K | $40M | ▲ 73% (+106K) | $132.07 | $390.28 (+196%) | 2026-03-31 |
| LOW Lowe's Companies Inc. | 0.7% | 171K | $40M | — | $210.44 | $182.12 (−13%) | 2026-03-31 |
Showing top 50 of 278 holdings by value.
FAQ ▾
What are EVENTIDE ASSET MANAGEMENT, LLC's largest holdings?
As of the latest 13F: Guardant Health, Inc. Common Stock 3.6%, Trane Technologies plc 2.8%, Lam Research Corp 2.4%, Mirum Pharmaceuticals, Inc. Common Stock 2.1%, Targa Resources Corp. 2.1%.
How big is EVENTIDE ASSET MANAGEMENT, LLC's 13F portfolio?
$6.0B across 278 disclosed U.S.-equity positions.
What is EVENTIDE ASSET MANAGEMENT, LLC's 3-year performance?
+56% (13F-replication, price return), -23 pts vs the S&P 500. Not an audited fund return.
Where does this data come from?
U.S. SEC Form 13F-HR institutional holdings filings.
Sourced from SEC Form 13F-HR filings · Not investment advice ▾
Data as of 2026-03-31 · Methodology
13F-replication (price return, filing-date based) — not an audited fund return.
Published by WealthFile · Not investment advice.
Latest activity = change vs. the prior 13F. Avg buy price = est. entry over the trailing 3 years (gain = vs. latest price). Returns are 13F-replication, not audited fund returns. Sourced from SEC 13F filings.