EA
EVENTIDE ASSET MANAGEMENT, LLC
EVENTIDE ASSET MANAGEMENT, LLC · Investor
1Y performance ⓘ
+47%
AUM (13F)
$6.0B
# of Holdings
278
3Y performance ⓘ
+59%
vs S&P 500 ⓘ
−12%
Updated
Mar 31
EVENTIDE ASSET MANAGEMENT, LLC's EVENTIDE ASSET MANAGEMENT, LLC holds 278 U.S.-equity positions worth $6.0B (SEC 13F, Q1 2026). Top positions: Guardant Health, Inc. Common Stock 3.6%, Trane Technologies plc 2.8%, Lam Research Corp 2.4%. 13F-replication return is +59% over 3 years (-12 pts vs the S&P 500) — a replicated, non-audited figure.
Holdings
| Stock | % of portfolio | Shares | Value | Latest activity | Avg buy price | Current price | Date |
|---|---|---|---|---|---|---|---|
| GH Guardant Health, Inc. Common Stock | 3.6% | 2.4M | $218M | ▼ 5.9% (−149K) | $23.44 | $128.83 (+450%) | 2026-03-31 |
| TT Trane Technologies plc | 2.8% | 407K | $169M | ▲ 0.8% (+3K) | $183.98 | $491.59 (+167%) | 2026-03-31 |
| LRCX Lam Research Corp | 2.4% | 688K | $147M | ▲ 2.9% (+19K) | $72.23 | $409.54 (+467%) | 2026-03-31 |
| MIRM Mirum Pharmaceuticals, Inc. Common Stock | 2.1% | 1.4M | $130M | ▼ 33% (−685K) | $24.02 | $107.77 (+349%) | 2026-03-31 |
| TRGP Targa Resources Corp. | 2.1% | 502K | $126M | ▲ 4.5% (+22K) | $72.95 | $264.51 (+263%) | 2026-03-31 |
| XMTR Xometry, Inc. Class A Common Stock | 2.0% | 3.0M | $121M | ▲ 0.8% (+24K) | $14.97 | $91.56 (+512%) | 2026-03-31 |
| GEV GE Vernova Inc. | 1.9% | 133K | $116M | ▼ 29% (−54K) | $328.94 | $1,127.59 (+243%) | 2026-03-31 |
| ODFL Old Dominion Freight Line | 1.9% | 592K | $115M | ▼ 3.1% (−19K) | $340.84 | $219.52 (−36%) | 2026-03-31 |
| SRRK Scholar Rock Holding Corporation Common Stock | 1.8% | 2.2M | $108M | ▼ 9.6% (−234K) | $18.80 | $49.19 (+162%) | 2026-03-31 |
| ARGX Argenx Se | 1.5% | 126K | $92M | ▲ 3.7% (+4K) | $372.58 | $903.75 (+143%) | 2026-03-31 |
| ASML Asml Hldg Nv | 1.5% | 68K | $90M | ▲ 1.9% (+1K) | $680.71 | $1,929.25 (+183%) | 2026-03-31 |
| IRTC iRhythm Holdings, Inc. Common Stock | 1.5% | 761K | $90M | ▲ 9.9% (+68K) | $124.03 | $104.69 (−16%) | 2026-03-31 |
| INSM Insmed, Inc. | 1.5% | 546K | $89M | ▲ 13% (+63K) | $17.05 | $98.61 (+478%) | 2026-03-31 |
| AXSM Axsome Therapeutics, Inc | 1.4% | 520K | $88M | ▼ 9.0% (−52K) | $69.89 | $247.85 (+255%) | 2026-03-31 |
| PCVX Vaxcyte, Inc. Common Stock | 1.3% | 1.4M | $80M | ▲ 50% (+457K) | $50.98 | $52.11 (+2%) | 2026-03-31 |
| ETR Entergy Corporation | 1.3% | 683K | $77M | ▲ 1.5% (+10K) | $75.82 | $112.20 (+48%) | 2026-03-31 |
| VST Vistra Corp. | 1.2% | 493K | $74M | ▲ 1.0% (+5K) | $33.18 | $167.26 (+404%) | 2026-03-31 |
| URI United Rentals, Inc. | 1.2% | 98K | $71M | ▲ 1.9% (+2K) | $626.71 | $1,092.68 (+74%) | 2026-03-31 |
| LBRT Liberty Energy Inc. | 1.1% | 2.4M | $69M | ▲ 22% (+433K) | $18.47 | $27.85 (+51%) | 2026-03-31 |
| TOST Toast, Inc. | 1.1% | 2.5M | $66M | — | $22.57 | $24.26 (+7%) | 2026-03-31 |
| MTD Mettler-Toledo International | 1.1% | 51K | $64M | ▲ 1.0% (+493) | $1,530.21 | $1,164.07 (−24%) | 2026-03-31 |
| MPWR Monolithic Power Systems, Inc. | 1.1% | 58K | $63M | ▼ 15% (−10K) | $500.54 | $1,537.88 (+207%) | 2026-03-31 |
| RPRX Royalty Pharma plc Class A Ordinary Shares | 1.0% | 1.3M | $63M | ▲ 1.2% (+16K) | $36.03 | $53.57 (+49%) | 2026-03-31 |
| NVT nVent Electric plc Ordinary Shares | 1.0% | 524K | $62M | ▲ 1.7% (+9K) | $42.94 | $184.34 (+329%) | 2026-03-31 |
| WMB Williams Companies Inc. | 1.0% | 832K | $61M | ▲ 4.9% (+39K) | $29.86 | $74.95 (+151%) | 2026-03-31 |
| NDAQ Nasdaq, Inc. Common Stock | 1.0% | 712K | $60M | ▲ 0.7% (+5K) | $54.67 | $82.61 (+51%) | 2026-03-31 |
| GNRC GENERAC HOLDINGS INC | 1.0% | 307K | $60M | ▲ 227% (+213K) | $108.01 | $295.54 (+174%) | 2026-03-31 |
| BBNX Beta Bionics, Inc. Common Stock | 1.0% | 5.9M | $60M | ▲ 19% (+951K) | $12.24 | $13.70 (+12%) | 2026-03-31 |
| DHI D.R. Horton Inc. | 1.0% | 431K | $59M | ▲ 0.9% (+4K) | $97.69 | $155.94 (+60%) | 2026-03-31 |
| KLAC KLA Corporation Common Stock | 1.0% | 40K | $58M | ▼ 12% (−6K) | $399.17 | $269.16 (−33%) | 2026-03-31 |
| BLTE Belite Bio Inc | 0.9% | 358K | $57M | ▼ 6.6% (−25K) | $74.00 | $147.07 (+99%) | 2026-03-31 |
| LSCC Lattice Semiconductor Corp | 0.9% | 611K | $57M | ▼ 1.6% (−10K) | $95.50 | $155.27 (+63%) | 2026-03-31 |
| PLD PROLOGIS, INC. | 0.9% | 427K | $56M | ▲ 1.5% (+6K) | $124.77 | $143.83 (+15%) | 2026-03-31 |
| TMDX TransMedics Group, Inc. Common Stock | 0.9% | 549K | $55M | — | $83.98 | $75.51 (−10%) | 2026-03-31 |
| DTM DT Midstream, Inc. | 0.9% | 402K | $54M | ▲ 1.8% (+7K) | $99.45 | $145.04 (+46%) | 2026-03-31 |
| NI NiSource Inc. | 0.9% | 1.1M | $53M | ▲ 0.9% (+10K) | $36.76 | $47.63 (+30%) | 2026-03-31 |
| KYMR Kymera Therapeutics, Inc. Common Stock | 0.9% | 627K | $52M | — | $40.20 | $99.45 (+147%) | 2026-03-31 |
| RBA RB Global, Inc. | 0.8% | 528K | $51M | — | $90.21 | $108.63 (+20%) | 2026-03-31 |
| WCN Waste Connections, Inc. | 0.8% | 310K | $50M | — | $139.07 | $153.43 (+10%) | 2026-03-31 |
| ORLY O'Reilly Automotive, Inc. | 0.8% | 540K | $50M | — | $848.98 | $85.63 (−90%) | 2026-03-31 |
| PWR Quanta Services, Inc. | 0.8% | 89K | $49M | ▲ 0.5% (+454) | $254.09 | $740.14 (+191%) | 2026-03-31 |
| COLL Collegium Pharmaceutical, Inc. Common Stock | 0.8% | 1.4M | $47M | ▼ 24% (−452K) | $23.99 | $33.45 (+39%) | 2026-03-31 |
| APGE Apogee Therapeutics, Inc. Common Stock | 0.8% | 557K | $47M | ▲ 28% (+121K) | $75.48 | $132.55 (+76%) | 2026-03-31 |
| VMC Vulcan Materials Company(Holding Company) | 0.8% | 170K | $46M | — | $233.30 | $304.39 (+30%) | 2026-03-31 |
| NVDA NVIDIA CORP | 0.7% | 259K | $45M | ▲ 8.4% (+20K) | $277.77 | $208.65 (−25%) | 2026-03-31 |
| EGP EastGroup Properties Inc. | 0.7% | 236K | $44M | — | $165.32 | $203.22 (+23%) | 2026-03-31 |
| IONS Ionis Pharmaceuticals, Inc. Common Stock | 0.7% | 575K | $43M | — | $35.74 | $75.89 (+112%) | 2026-03-31 |
| STE STERIS plc | 0.7% | 195K | $43M | ▲ 2.2% (+4K) | $191.28 | $200.40 (+5%) | 2026-03-31 |
| PANW Palo Alto Networks, Inc. Common Stock | 0.7% | 252K | $40M | ▲ 73% (+106K) | $199.74 | $286.40 (+43%) | 2026-03-31 |
| LOW Lowe's Companies Inc. | 0.7% | 171K | $40M | — | $199.97 | $214.40 (+7%) | 2026-03-31 |
Showing top 50 of 278 holdings by value.
FAQ ▾
What are EVENTIDE ASSET MANAGEMENT, LLC's largest holdings?
As of the latest 13F: Guardant Health, Inc. Common Stock 3.6%, Trane Technologies plc 2.8%, Lam Research Corp 2.4%, Mirum Pharmaceuticals, Inc. Common Stock 2.1%, Targa Resources Corp. 2.1%.
How big is EVENTIDE ASSET MANAGEMENT, LLC's 13F portfolio?
$6.0B across 278 disclosed U.S.-equity positions.
What is EVENTIDE ASSET MANAGEMENT, LLC's 3-year performance?
+59% (13F-replication, price return), -12 pts vs the S&P 500. Not an audited fund return.
Where does this data come from?
U.S. SEC Form 13F-HR institutional holdings filings.
Sourced from SEC Form 13F-HR filings · Not investment advice ▾
Data as of 2026-03-31 · Methodology
13F-replication (price return, filing-date based) — not an audited fund return.
Published by WealthFile · Not investment advice.
Latest activity = change vs. the prior 13F. Avg buy price = est. entry over the trailing 3 years (gain = vs. latest price). Returns are 13F-replication, not audited fund returns. Sourced from SEC 13F filings.